Malaria Prevention in Ghana — 2026 Guide

Ghana has a high malaria burden, with transmission occurring across the entire country year-round. Malaria is the leading cause of outpatient visits in Ghanaian health facilities, and every traveller must use antimalarials and bite prevention measures.

Critical Warning: Malaria transmission occurs throughout Ghana, in all regions, at all altitudes. Risk is highest during and immediately after the rainy seasons (May–October in the south, June–October in the north).

Malaria Risk by Region

Ghana experiences stable, high malaria transmission countrywide. The southern coastal belt has two rainy seasons, meaning year-round elevated risk. The northern savannah has a single intense rainy season.

RegionRisk LevelPeak SeasonNotes
Greater Accra & Coastal BeltHighMay – Jul, Sep – NovTwo rainy seasons; urban breeding sites in drains and lagoons
Ashanti Region (Kumasi)Very HighMay – OctForest zone, high humidity, significant year-round transmission
Western & Central Regions (Cape Coast)Very HighMay – OctTropical rainforest, consistently high mosquito density
Eastern & Volta RegionsVery HighApr – OctLake Volta region creates extensive breeding habitat
Northern Region (Tamale)HighJun – OctSingle intense rainy season, savannah zone
Upper East & Upper WestHighJun – OctGuinea savannah; seasonal but intense during rains

Key fact: Ghana reports approximately 5.3 million confirmed malaria cases and over 12,500 deaths annually (Ghana Health Service 2024). Malaria accounts for ~30% of all outpatient visits. Plasmodium falciparum is responsible for 98% of cases.

Antimalarial Medication Comparison

Start your antimalarials before arriving in Ghana. Visit a travel clinic at least 4–6 weeks before departure.

MedicationDosingStartContinue After ReturnUK Cost (approx.)US Cost (approx.)Common Side Effects
Malarone
(Atovaquone/Proguanil)
1 tablet daily 1–2 days before 7 days £40–£80 (2 weeks) $60–$150 (2 weeks) Nausea, headache, abdominal pain (generally mild)
Doxycycline 100mg daily 1–2 days before 28 days £5–£15 (4 weeks) $10–$30 (4 weeks) Sun sensitivity (important in Ghana!), stomach upset, thrush
Mefloquine
(Lariam)
1 tablet weekly 2–3 weeks before 4 weeks £15–£30 (4 weeks) $40–$80 (4 weeks) Vivid dreams, dizziness, anxiety (trial before travel)
Note for Ghana: If taking Doxycycline, be extra cautious about sun exposure — Ghana sits close to the equator with intense UV. Use SPF 50+ and cover up during peak sun hours. Malarone is the preferred choice for short trips (1–3 weeks).

Prevention Methods

1. Insect Repellent (DEET-based)

  • Apply 30–50% DEET repellent on exposed skin, especially ankles, wrists, and neck
  • Available brands in Ghana: OFF!, Peaceful Sleep (locally popular), Jungle Formula
  • Reapply every 4–6 hours; more frequently if sweating in Ghana’s tropical heat
  • Picaridin 20% is an effective DEET alternative with less skin irritation

2. Mosquito Nets

  • Use an insecticide-treated net (ITN) every night — Ghana distributes millions of Long-Lasting Insecticidal Nets (LLINs) nationally
  • Budget guesthouses may not provide nets; carry your own travel-size net
  • Check for tears and ensure full enclosure before sleeping

3. Protective Clothing

  • Cover arms and legs from dusk (6pm) to dawn (6am)
  • Loose-fitting, light-coloured cotton works best in Ghana’s heat
  • Spray clothing with permethrin for additional barrier protection

4. Environmental Precautions

  • Choose accommodation with screened windows or air conditioning
  • Use mosquito coils or electric plug-in vaporisers (widely sold in Ghana)
  • Avoid areas near stagnant water, open drains, and Lake Volta shores at dusk

Recognising Malaria Symptoms

Symptoms may appear 7 days to 12 months after exposure. Ghana’s dominant species, P. falciparum, causes the most severe form of malaria.

Early Symptoms

  • Cyclic fever with chills and sweating
  • Severe headache, body aches
  • Nausea, vomiting, loss of appetite
  • Fatigue and weakness
  • Mild jaundice in some cases

Severe Malaria (Emergency)

  • Confusion, disorientation
  • Seizures or convulsions
  • Respiratory distress
  • Dark/cola-coloured urine
  • Severe anaemia
  • Prostration (unable to sit/stand)
Important: Any fever during or after travel to Ghana must be investigated for malaria — tell your doctor about your travel history even months after returning home.

Emergency Treatment in Ghana

Ghana has a well-established malaria treatment infrastructure:

  1. Rapid Diagnostic Tests (RDTs) are available at pharmacies, clinics, and even some chemical shops for GH¢10–30 (~$0.80–$2.50)
  2. ACT treatment (Artemether-Lumefantrine) is the first-line therapy in Ghana
  3. Severe cases require IV artesunate at a hospital
  4. Do not rely on chloroquine — high resistance levels in Ghana

Hospitals for Travellers

CityHospitalPhone
AccraKorle Bu Teaching Hospital+233 30 266 5401
AccraNyaho Medical Centre (private)+233 30 277 5341
KumasiKomfo Anokye Teaching Hospital+233 32 202 2301
TamaleTamale Teaching Hospital+233 37 202 2455
Cape CoastCape Coast Teaching Hospital+233 33 213 2040

Children & Pregnant Women

Children

  • Children under 5 account for the majority of malaria deaths in Ghana
  • Malarone paediatric tablets available for children ≥5kg
  • Doxycycline is not recommended under age 12 (affects developing teeth and bones)
  • Use 20–30% DEET for children; avoid applying to small children’s hands
  • Ghana’s Seasonal Malaria Chemoprevention (SMC) programme covers children in the north

Pregnant Women

  • Travel authorities advise against non-essential travel to Ghana during pregnancy
  • Malaria in pregnancy can cause miscarriage, stillbirth, severe anaemia, and low birth weight
  • Mefloquine is the only antimalarial approved for all three trimesters
  • Doxycycline is contraindicated in pregnancy; Malarone lacks sufficient safety data

Malaria Statistics — Ghana

Annual confirmed cases~5.3 million (Ghana Health Service 2024)
Annual deaths~12,500 (WHO 2024)
Share of outpatient visits~30% of all hospital presentations
Predominant speciesPlasmodium falciparum (98%)
Peak transmissionMay – October (rainy season)
Transmission typeStable, year-round, entire country
WHO classificationHigh burden / High transmission

Emergency Numbers

  • Emergency: 112 / 999
  • Ambulance: 193
  • Fire: 192
  • Police: 191